Nyamavhuvhu 17, 2015 |Zviridzwa nemidziyo, Zvishandiso zveLabhoritari nemidziyo yemurabhoritari, Nhau dzeLabhoritari, Matanho emuLabhoritari, Utachiona hwerabhoritari, kuyedzwa kweLabhoritari.
Nekuisa ichi chisingadhuri-chishandiso chimwe chete, chakagadzirwa paYunivhesiti yeWisconsin-Madison, paruoko kana mudumbu, varwere vanogona kutora ropa ravo pamba mumaminitsi.
Kweanopfuura makore maviri, vezvenhau vekuAmerica vanga vachifadzwa nepfungwa yeTheranos CEO Elizabeth Holmes yekupa varwere vanoda kuongororwa ropa ongororo yeropa pachigunwe pane venipuncture.Zvichakadaro, maLab ekutsvagisa munyika yose ari kushanda kugadzira nzira dzekuunganidza masampula ekuongororwa kwerabhoritari yekurapa asingade tsono zvachose.
Nekuedza kwakadaro, inogona kupinda mumusika nekukurumidza.Ichi chishandiso chekuunganidza ropa chisina tsono chinodaidzwa kuti HemoLink, chakagadzirwa nechikwata chekutsvagisa paYunivhesiti yeWisconsin-Madison.Vashandisi vanongoisa mudziyo wegorofu paruoko kana mudumbu kwemaminetsi maviri.Munguva iyi, chigadziro chinokwevera ropa kubva mumapillari mumudziyo muduku.Murwere anobva atumira chubhu yeropa rakaunganidzwa kurabhoritari yezvokurapa kunoongororwa.
Iyi yakachengeteka mudziyo wakanakira vana.Nekudaro, varwere vanoda kugara vachiongororwa ropa kuti vatarise hutano hwavo vanozobatsirwawo sezvo zvichivaponesa kubva pakufamba nzendo kuenda kumakiriniki marabhu kunodhonza ropa nenzira yechinyakare tsono.
Mukuita kunonzi "capillary action," HemoLink inoshandisa microfluidics kugadzira diki vacuum inokwevera ropa kubva mumacapillaries kuburikidza nediki nzira muganda mumachubhu, Gizmag inoshuma.Chigadzirwa chacho chinounganidza 0.15 cubic masentimita eropa, iyo yakakwana kuona cholesterol, zvirwere, kenza masero, shuga yeropa uye mamwe mamiriro.
Pathologists nenyanzvi dzemakiriniki lab vachange vachiona kuvhurwa kwekupedzisira kweHemoLink kuti vaone kuti vagadziri vayo vanokunda sei matambudziko anokanganisa bvunzo dzerabhoritari izvo zvinogona kukonzerwa neiyo interstitial fluid iyo inowanzo perekedza ropa recapillary pakuunganidza masampuli akadai.Kuti tekinoroji yekuyedza lab inoshandiswa neTheranos inogona kugadzirisa sei dambudziko rimwe chete rave rakatariswa nemarabhu ekurapa.
Tasso Inc., yekutanga yekurapa yakagadzira HemoLink, yakavambwa nevatatu vaimbove UW-Madison microfluidics vaongorori:
Casavant inotsanangura chikonzero nei masimba emicrofluidic achishanda: “Pamwero uyu, kusimba kwepamusoro kunokosha kupfuura simba rinokwevera zvinhu pasi, uye kunoita kuti ropa rirambe riri mugwara pasinei nokuti wakabata sei mudziyo wacho,” akadaro mushumo weGizmag.
Chirongwa ichi chakatsigirwa nemadhora mazana matatu emadhora neDefence Advanced Research Projects Agency (DARPA), ruoko rwekutsvagisa rweUnited States Department of Defense (DOD).
Vatatu vatsigiri veTasso, Inc., vaimbova vatsvakurudzi vemicrofluidics paYunivhesiti yeWisconsin-Madison (kubva kuruboshwe kuenda kurudyi): Ben Casavant, Mutevedzeri weMutungamiri weKushanda uye Injiniya, Erwin Berthier, Mutevedzeri weMutungamiri weKutsvakurudza uye Kubudirira uye Technology, uye Ben Moga, Mutungamiriri, muchitoro chekofi vakabata iyo HemoLink pfungwa.(Mufananidzo wekodzero yekodzero Tasso, Inc.)
Iyo HemoLink mudziyo yakachipa kugadzira uye Tasso inotarisira kuita kuti iwanikwe kune vatengi muna 2016, maererano neGizmag.Nekudaro, izvi zvinogona kuenderana nekuti Tasso masayendisiti anogona kugadzira nzira yekuona kugadzikana kwemasampuli eropa.
Parizvino, masampuli eropa mazhinji ekuongororwa murabhoritari yekiriniki anoda kutakurwa mucheni inotonhora.Maererano neshumo yeGizmag, masayendisiti eTasso anoda kuchengetedza masampuli eropa pa140 degrees Fahrenheit kwevhiki kuti ave nechokwadi chekuti anoongororwa kana vasvika kukiriniki lab kuti igadziriswe.Tasso anoronga kunyorera mvumo yeUS Food and Drug Administration (FDA) mukupera kwegore rino.
HemoLink, inodhura yakaderera inoraswa isina needleless yekuunganidza ropa mudziyo, inogona kuwanikwa kune vatengi muna 2016. Inoshandisa nzira inonzi "capillary action" kutora ropa muchubhu yekuunganidza.Vashandisi vanongoiisa paruoko kana mudumbu kwemaminetsi maviri, mushure mezvo iyo chubhu inotumirwa kune yekurapa lab kuti iongororwe.(Mufananidzo wekodzero yekodzero Tasso, Inc.)
HemoLink inhau huru kune vanhu vasingade tsono uye vanobhadhara vane hanya nekudzikisa mutengo wehutano.Pamusoro pezvo, kana Tasso ikabudirira uye ikatenderwa neFDA, inogona kupawo vanhu pasirese - kunyangwe munzvimbo dziri kure - nekukwanisa kubatana nepakati pekuongorora ropa maLab uye kubatsirwa kubva mukuongororwa kwepamusoro.
"Tine data rinomanikidza, timu ine hukasha manejimendi uye zvisingaite zvekiriniki zvinodiwa mumusika uri kukura," Modja akadaro mumushumo weGizmag."Kuwedzera kuchengetwa kwemba nekuchengetedzeka uye kuri nyore kuunganidzwa kweropa rekuongororwa kwekiriniki uye kutarisa imhando yehunyanzvi inogona kuvandudza mhedzisiro pasina kuwedzera mari yehutano."
Asi havazi vese vane chekuita muindasitiri yerabhoritari yekurapa vachanakidzwa nekuvhurwa kwemusika weHemoLink.Iyo inogona kushandura-mutambo tekinoroji kune ese ari maviri ekiriniki marabhoritari uye yeSilicon Valley biotech kambani Theranos, iyo yakashandisa mamirioni emadhora kugadzirisa nzira yainoongorora yakaoma ropa kubva kumunwe weropa samples, USA TODAY inoshuma.
Zvingave zvinokatyamadza kana vagadziri veHemoLink vakagona kugadzirisa chero nyaya nehunyanzvi hwavo, kuwana mvumo yeFDA, uye kuunza kutengesa chigadzirwa mukati memwedzi makumi maviri nemana inotevera izvo zvinobvisa kudiwa kwevenipuncture uye sampling yemunwe.Mhando dzakawanda dzekuongororwa kwerabhoritari yekurapa.Izvi ndezvechokwadi kubira "kutinhira" kubva kuTheranos, iyo kwemakore maviri apfuura yanga ichiratidzira chiono chekuvandudza indasitiri yekuongorora lab yekiriniki sezvairi kushanda nhasi.
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Ko Theranos inogona kushandura musika wekuongororwa kwekiriniki marabhoritari?Chinangwa chekutarisa kusimba, mabasa uye matambudziko anofanirwa kugadziriswa
handisi kunzwisisa zviri kuitika pano.Kana ikakwevera ropa kuburikidza neganda, haigadziri nzvimbo yeropa, inonziwo hickey?Ganda rine avascular, saka rinozviita sei?Pane anogona here kutsanangura zvimwe zvezvesainzi zviri seri kweizvi?Ndinofunga ipfungwa huru… asi ndinoda kuziva zvakawanda.Ndatenda
Handina chokwadi chekuti izvi zvinoshanda sei - Theranos haiburitse ruzivo rwakawanda.Mumazuva mashoma apfuura, vakatambirawo zviziviso zvekumira nekurega.Manzwisisiro angu emidziyo iyi ndeyekuti anoshandisa high-density "clumps" ye capillaries inoita sematsono.Vanogona kusiya zvigamba zvishoma, asi handifungi kuti kupinda mukati meganda kwakadzika setsono (eg Akkuchek).